Sequence Detail

ID/Version

Q3TN34 Q3TPY3 Q3UB65 (UniProt | EBI)

Last sequence update: 2005-10-11
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=MICAL-like protein 2;AltName: Full=Junctional Rab13-binding protein;AltName: Full=Molecule interacting with CasL-like 2; Short=MICAL-L2;

Provider

SWISS-PROT

Sequence

Polypeptide 1009 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Micall2	MICAL-like 2	45	98	4	4

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:112525 Terai T, et al., JRAB/MICAL-L2 is a junctional Rab13-binding protein mediating the endocytic recycling of occludin. Mol Biol Cell. 2006 May;17(5):2465-75
J:136002 Nakatsuji H, et al., Involvement of actinin-4 in the recruitment of JRAB/MICAL-L2 to cell-cell junctions and the formation of functional tight junctions. Mol Cell Biol. 2008 May;28(10):3324-35
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:200380 Sakane A, et al., Rab13 regulates neurite outgrowth in PC12 cells through its effector protein, JRAB/MICAL-L2. Mol Cell Biol. 2010 Feb;30(4):1077-87
J:200405 Yamamura R, et al., The interaction of JRAB/MICAL-L2 with Rab8 and Rab13 coordinates the assembly of tight junctions and adherens junctions. Mol Biol Cell. 2008 Mar;19(3):971-83
J:201396 Sakane A, et al., Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins. Genes Cells. 2013 Sep;18(9):810-22
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:359823 Sakane A, et al., JRAB/MICAL-L2 undergoes liquid-liquid phase separation to form tubular recycling endosomes. Commun Biol. 2021 May 11;4(1):551