Sequence Detail

ID/Version

Q3TIW9 A2A5N7 D3Z6V6 (UniProt | EBI)

Last sequence update: 2005-10-11
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 {ECO:0000305}; Short=E-NPP 7; Short=NPP-7; EC=3.1.4.12 {ECO:0000269|PubMed:21177474};AltName: Full=Alkaline sphingomyelin phosphodiesterase;AltName: Ful

Provider

SWISS-PROT

Sequence

Polypeptide 439 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Enpp7	ectonucleotide pyrophosphatase/phosphodiesterase 7	32	96	4	3

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:170667 Zhang Y, et al., Crucial role of alkaline sphingomyelinase in sphingomyelin digestion: a study on enzyme knockout mice. J Lipid Res. 2011 Apr;52(4):771-81
J:211198 Zhang P, et al., Alkaline sphingomyelinase (NPP7) promotes cholesterol absorption by affecting sphingomyelin levels in the gut: A study with NPP7 knockout mice. Am J Physiol Gastrointest Liver Physiol. 2014 May 15;306(10):G903-8