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Sequence Detail
ID/Version
Q3TCJ1 Q3TB08 Q8K0R4 (UniProt | EBI) Last sequence update: 2005-10-11
Last annotation update: 2025-02-05
Sequence
description
from provider
RecName: Full=BRISC complex subunit Abraxas 2 {ECO:0000312|MGI:MGI:1926116};AltName: Full=Abraxas brother protein 1;AltName: Full=Protein FAM175B;
Provider SWISS-PROT
Sequence
Polypeptide 415 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Abraxas2 BRISC complex subunit 52 96 3 14
Sequence references in MGI J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:193213 Ambivero CT, et al., ATF4 interacts with Abro1/KIAA0157 scaffold protein and participates in a cytoprotective pathway. Biochim Biophys Acta. 2012 Dec;1823(12):2149-56
J:203788 Zheng H, et al., A BRISC-SHMT complex deubiquitinates IFNAR1 and regulates interferon responses. Cell Rep. 2013 Oct 17;5(1):180-93
J:227379 Cilenti L, et al., Regulation of Abro1/KIAA0157 during myocardial infarction and cell death reveals a novel cardioprotective mechanism for Lys63-specific deubiquitination. J Mol Cell Cardiol. 2011 Apr;50(4):652-61
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory