Sequence Detail

ID/Version

Q3LRV9 E9Q825 Q3LRW0 A6XA78 (UniProt | EBI)

Last sequence update: 2005-10-25
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Trem-like transcript 4 protein; Short=TLT-4;AltName: Full=Triggering receptor expressed on myeloid cells-like protein 3;AltName: Full=Triggering receptor expressed on myeloid cells-like protein 4;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 263 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Treml4	triggering receptor expressed on myeloid cells-like 4	21	96	2	5

Sequence references in MGI

J:144335 Hemmi H, et al., A new triggering receptor expressed on myeloid cells (Trem) family member, Trem-like 4, binds to dead cells and is a DNAX activation protein 12-linked marker for subsets of mouse macrophages and dendritic cells. J Immunol. 2009 Feb 1;182(3):1278-86
J:180744 Hemmi H, et al., Treml4, an Ig superfamily member, mediates presentation of several antigens to T cells in vivo, including protective immunity to HER2 protein. J Immunol. 2012 Feb 1;188(3):1147-55
J:231858 Ramirez-Ortiz ZG, et al., The receptor TREML4 amplifies TLR7-mediated signaling during antiviral responses and autoimmunity. Nat Immunol. 2015 May;16(5):495-504