Sequence Detail

ID/Version

Q2VPA6 Q640L4 Q8R4K9 Q2VPA7 Q8BWI5 (UniProt | EBI)

Last sequence update: 2006-10-31
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Helicase POLQ-like {ECO:0000305}; EC=3.6.4.12 {ECO:0000250|UniProtKB:Q8TDG4};AltName: Full=Mus308-like helicase {ECO:0000303|PubMed:11751861};AltName: Full=POLQ-like helicase {ECO:0000303|PubMed:11751861};

Provider

SWISS-PROT

Sequence

Polypeptide 1069 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Helq	helicase, POLQ-like	22	96	3	8

Sequence references in MGI

J:75194 Marini F, et al., A Human DNA Helicase Homologous to the DNA Cross-link Sensitivity Protein Mus308. J Biol Chem. 2002 Mar 8;277(10):8716-23
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:206104 Adelman CA, et al., HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis. Nature. 2013 Oct 17;502(7471):381-4
J:211173 Luebben SW, et al., Helq acts in parallel to Fancc to suppress replication-associated genome instability. Nucleic Acids Res. 2013 Dec;41(22):10283-97
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89