Sequence Detail

ID/Version

Q2LKU9 Q67EY4 M4TJP5 M4T3K8 Q3U0B5 M4T4C8 M4T632 (UniProt | EBI)

Last sequence update: 2006-02-21
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=NACHT, LRR and PYD domains-containing protein 1a; EC=3.4.-.- {ECO:0000250|UniProtKB:Q9C000};AltName: Full=Caspase recruitment domain-containing protein 7;AltName: Full=Death effector filament-forming ced-4-like apoptosis protein;AltN

Provider

SWISS-PROT

Sequence

Polypeptide 1182 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nlrp1a	NLR family, pyrin domain containing 1A	81	96	4	13

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:99748 Boyden ED, et al., Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin. Nat Genet. 2006;38(2):240-244
J:191055 Masters SL, et al., NLRP1 Inflammasome Activation Induces Pyroptosis of Hematopoietic Progenitor Cells. Immunity. 2012 Dec 14;37(6):1009-23
J:194517 Sastalla I, et al., Transcriptional analysis of the three Nlrp1 paralogs in mice. BMC Genomics. 2013 Mar 18;14(1):188