Sequence Detail

ID/Version

Q18PI6 Q3TBT1 Q9Z178 Q8BFV0 Q3U0A2 Q18PI7 (UniProt | EBI)

Last sequence update: 2006-07-25
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=SLAM family member 5;AltName: Full=Leukocyte differentiation antigen CD84;AltName: Full=Signaling lymphocytic activation molecule 5;AltName: CD_antigen=CD84;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 329 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cd84	CD84 antigen	28	98	3	17

Sequence references in MGI

J:53891 de la Fuente MA, et al., Molecular cloning, characterization, and chromosomal localization of the mouse homologue of CD84, a member of the CD2 family of cell surface molecules. Immunogenetics. 1999 Apr;49(4):249-55
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:123938 Nanda N, et al., Platelet aggregation induces platelet aggregate stability via SLAM family receptor signaling. Blood. 2005 Nov 1;106(9):3028-34
J:157915 Cannons JL, et al., Optimal germinal center responses require a multistage T cell:B cell adhesion process involving integrins, SLAM-associated protein, and CD84. Immunity. 2010 Feb 26;32(2):253-65
J:166054 Wang N, et al., Cutting edge: The adapters EAT-2A and -2B are positive regulators of CD244- and CD84-dependent NK cell functions in the C57BL/6 mouse. J Immunol. 2010 Nov 15;185(10):5683-7
J:227381 Sintes J, et al., Mouse CD84 is a pan-leukocyte cell-surface molecule that modulates LPS-induced cytokine secretion by macrophages. J Leukoc Biol. 2010 Oct;88(4):687-97
J:244548 Wong EB, et al., B cell-intrinsic CD84 and Ly108 maintain germinal center B cell tolerance. J Immunol. 2015 May 01;194(9):4130-43
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89