Sequence Detail

ID/Version

Q14B80 (UniProt | EBI)

Last sequence update: 2006-08-22
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Potassium voltage-gated channel subfamily C member 2 {ECO:0000312|MGI:MGI:96668};AltName: Full=Shaw-like potassium channel {ECO:0000250|UniProtKB:P22462};AltName: Full=Voltage-gated potassium channel Kv3.2 {ECO:0000303|PubMed:12000114};

Provider

SWISS-PROT

Sequence

Polypeptide 642 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Kcnc2	potassium voltage gated channel, Shaw-related subfamily, member 2	69	105	3	7

Sequence references in MGI

J:66730 Lau D, et al., Impaired fast-spiking, suppressed cortical inhibition, and increased susceptibility to seizures in mice lacking kv3.2 K+ channel proteins. J Neurosci. 2000 Dec 15;20(24):9071-85
J:92649 Ozaita A, et al., A unique role for Kv3 voltage-gated potassium channels in starburst amacrine cell signaling in mouse retina. J Neurosci. 2004 Sep 18;24(33):7335-43
J:140824 Kasten MR, et al., Differential regulation of action potential firing in adult murine thalamocortical neurons by Kv3.2, Kv1, and SK potassium and N-type calcium channels. J Physiol. 2007 Oct 15;584(Pt 2):565-82
J:169868 Kudo T, et al., Fast delayed rectifier potassium current: critical for input and output of the circadian system. J Neurosci. 2011 Feb 23;31(8):2746-55
J:186741 Boda E, et al., Brain expression of Kv3 subunits during development, adulthood and aging and in a murine model of Alzheimer's disease. J Mol Neurosci. 2012 Mar;46(3):606-15
J:219112 Chow A, et al., K(+) channel expression distinguishes subpopulations of parvalbumin- and somatostatin-containing neocortical interneurons. J Neurosci. 1999 Nov 1;19(21):9332-45
J:219188 Tansey EP, et al., Developmental expression of potassium-channel subunit Kv3.2 within subpopulations of mouse hippocampal inhibitory interneurons. Hippocampus. 2002;12(2):137-48
J:244251 Harvey M, et al., Impaired long-range synchronization of gamma oscillations in the neocortex of a mouse lacking Kv3.2 potassium channels. J Neurophysiol. 2012 Aug 01;108(3):827-33
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89