Sequence Detail

ID/Version

Q0VGT2 E9PYJ4 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Zinc finger protein GLI2 {ECO:0000305};AltName: Full=Tax helper protein {ECO:0000250|UniProtKB:P10070};

Provider

SWISS-PROT

Sequence

Polypeptide 1544 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Gli2	GLI-Kruppel family member GLI2	165	200	4	168

Sequence references in MGI

J:38381 Mo R, et al., Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development. Development. 1997 Jan;124(1):113-23
J:56563 Sasaki H, et al., Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling. Development. 1999 Sep;126(17):3915-24
J:113893 Murone M, et al., Gli regulation by the opposing activities of fused and suppressor of fused. Nat Cell Biol. 2000 May;2(5):310-2
J:114033 Koyabu Y, et al., Physical and functional interactions between Zic and Gli proteins. J Biol Chem. 2001 Mar 9;276(10):6889-92
J:189074 Li ZJ, et al., Kif7 regulates Gli2 through Sufu-dependent and -independent functions during skin development and tumorigenesis. Development. 2012 Nov;139(22):4152-61
J:218232 Chong YC, et al., Bifurcating action of Smoothened in Hedgehog signaling is mediated by Dlg5. Genes Dev. 2015 Feb 1;29(3):262-76
J:221866 Yoshida M, et al., The transcription factor Foxc1 is necessary for Ihh-Gli2-regulated endochondral ossification. Nat Commun. 2015;6:6653
J:228951 Han B, et al., FOXC1 Activates Smoothened-Independent Hedgehog Signaling in Basal-like Breast Cancer. Cell Rep. 2015 Nov 3;13(5):1046-58