Sequence Detail

ID/Version

Q0VBL6 Q9QX54 A1IM61 Q8VHR1 Q9Z2I5 E9QLB1 Q3UN40 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Hypoxia-inducible factor 3-alpha {ECO:0000303|PubMed:9840812}; Short=HIF-3-alpha; Short=HIF3-alpha;AltName: Full=Basic-helix-loop-helix-PAS protein MOP7;AltName: Full=HIF3-alpha-1;AltName: Full=Inhibitory PAS domain protein {

Provider

SWISS-PROT

Sequence

Polypeptide 662 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Hif3a	hypoxia inducible factor 3, alpha subunit	47	106	3	8

Sequence references in MGI

J:62516 Gu YZ, et al., Molecular characterization and chromosomal localization of a third alpha-class hypoxia inducible factor subunit, HIF3alpha. Gene Expr. 1998;7(3):205-13
J:73190 Makino Y, et al., Inhibitory PAS domain protein is a negative regulator of hypoxia-inducible gene expression. Nature. 2001 Nov 29;414(6863):550-4
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:132655 Yamashita T, et al., Abnormal heart development and lung remodeling in mice lacking the hypoxia-inducible factor-related basic helix-loop-helix PAS protein NEPAS. Mol Cell Biol. 2008 Feb;28(4):1285-97
J:203396 Torii S, et al., Pro-apoptotic activity of inhibitory PAS domain protein (IPAS), a negative regulator of HIF-1, through binding to pro-survival Bcl-2 family proteins. Cell Death Differ. 2011 Nov;18(11):1711-25