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Sequence Detail
Q0VBD0 (UniProt | EBI) Last sequence update: 2006-09-05
Last annotation update: 2019-12-11
from provider
RecName: Full=Integrin beta-8 {ECO:0000305};Flags: Precursor;
Polypeptide 767 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Itgb8 integrin beta 8 26 76 9 4
Sequence references in MGI J:77682 Zhu J, et al., beta8 integrins are required for vascular morphogenesis in mouse embryos. Development. 2002 Jun;129(12):2891-903
J:102190 Proctor JM, et al., Vascular development of the brain requires beta8 integrin expression in the neuroepithelium. J Neurosci. 2005 Oct 26;25(43):9940-8
J:244456 Edwards JP, et al., Release of active TGF-beta1 from the latent TGF-beta1/GARP complex on T regulatory cells is mediated by integrin beta8. J Immunol. 2014 Sep 15;193(6):2843-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory