Sequence Detail

ID/Version

Q0VBD0 (UniProt | EBI)

Last sequence update: 2006-09-05
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Integrin beta-8 {ECO:0000305};Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 767 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Itgb8	integrin beta 8	47	106	3	7

Sequence references in MGI

J:77682 Zhu J, et al., beta8 integrins are required for vascular morphogenesis in mouse embryos. Development. 2002 Jun;129(12):2891-903
J:102190 Proctor JM, et al., Vascular development of the brain requires beta8 integrin expression in the neuroepithelium. J Neurosci. 2005 Oct 26;25(43):9940-8
J:244456 Edwards JP, et al., Release of active TGF-beta1 from the latent TGF-beta1/GARP complex on T regulatory cells is mediated by integrin beta8. J Immunol. 2014 Sep 15;193(6):2843-9