Sequence Detail

ID/Version

Q0GGX2 B2RXS6 (UniProt | EBI)

Last sequence update: 2006-10-03
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Zinc finger protein 541;AltName: Full=Spermatogenic cell HDAC-interacting protein 1 {ECO:0000303|PubMed:18849567};

Provider

SWISS-PROT

Sequence

Polypeptide 1363 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Zfp541	zinc finger protein 541	18	98	3	10

Sequence references in MGI

J:125967 Choi E, et al., Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library. BMC Genomics. 2007;8:256
J:144592 Choi E, et al., A novel germ cell-specific protein, SHIP1, forms a complex with chromatin remodeling activity during spermatogenesis. J Biol Chem. 2008 Dec 12;283(50):35283-94
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306305 Oura S, et al., KCTD19 and its associated protein ZFP541 are independently essential for meiosis in male mice. PLoS Genet. 2021 May;17(5):e1009412
J:307864 Horisawa-Takada Y, et al., Meiosis-specific ZFP541 repressor complex promotes developmental progression of meiotic prophase towards completion during mouse spermatogenesis. Nat Commun. 2021 Jun 1;12(1):3184
J:324909 Xu J, et al., ZFP541 maintains the repression of pre-pachytene transcriptional programs and promotes male meiosis progression. Cell Rep. 2022 Mar 22;38(12):110540
J:338159 Li Y, et al., The ZFP541-KCTD19 complex is essential for pachytene progression by activating meiotic genes during mouse spermatogenesis. J Genet Genomics. 2022 Nov;49(11):1029-1041