Sequence Detail

ID/Version

Q09324 O35981 Q8BRB2 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase; EC=2.4.1.102 {ECO:0000269|PubMed:22056345};AltName: Full=Core 2 beta-1,6-N-acetylglucosaminyltransferase {ECO:0000303|PubMed:9881978}; Shor

Provider

SWISS-PROT

Sequence

Polypeptide 428 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Gcnt1	glucosaminyl (N-acetyl) transferase 1, core 2	25	102	2	25

Sequence references in MGI

J:43585 Sekine M, et al., Tissue-specific regulation of mouse core 2 beta-1,6-N-acetylglucosaminyltransferase. J Biol Chem. 1997 Oct 24;272(43):27246-52
J:86387 Ellies LG, et al., Core 2 oligosaccharide biosynthesis distinguishes between selectin ligands essential for leukocyte homing and inflammation. Immunity. 1998 Dec;9(6):881-90
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:320156 Yen TY, et al., Highly conserved cysteines of mouse core 2 beta1,6-N-acetylglucosaminyltransferase I form a network of disulfide bonds and include a thiol that affects enzyme activity. J Biol Chem. 2003 Nov 14;278(46):45864-81
J:320698 Pak JE, et al., Structural and mechanistic characterization of leukocyte-type core 2 beta1,6-N-acetylglucosaminyltransferase: a metal-ion-independent GT-A glycosyltransferase. J Mol Biol. 2011 Dec 16;414(5):798-811