Sequence Detail

ID/Version

Q09200 (UniProt | EBI)

Last sequence update: 1995-11-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Beta-1,4 N-acetylgalactosaminyltransferase 1 {ECO:0000305}; EC=2.4.1.92 {ECO:0000269|PubMed:8855236};AltName: Full=(N-acetylneuraminyl)-galactosylglucosylceramide;AltName: Full=GM2/GD2 synthase {ECO:0000303|PubMed:8855236};AltName: F

Provider

SWISS-PROT

Sequence

Polypeptide 533 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	B4galnt1	beta-1,4-N-acetyl-galactosaminyl transferase 1	33	102	4	5

Sequence references in MGI

J:22416 Takamiya K, et al., T cell receptor-mediated stimulation of mouse thymocytes induces up-regulation of the GM2/GD2 synthase gene. FEBS Lett. 1995 Jan 16;358(1):79-83
J:26188 Sango K, et al., beta-1,4-N-Acetylgalactosaminyltransferase involved in ganglioside synthesis: cDNA sequence, expression, and chromosome mapping of the mouse gene. Genomics. 1995 May 20;27(2):362-5
J:35787 Takamiya K, et al., Mice with disrupted GM2/GD2 synthase gene lack complex gangliosides but exhibit only subtle defects in their nervous system. Proc Natl Acad Sci U S A. 1996 Oct 1;93(20):10662-7
J:100940 Pan B, et al., Myelin-associated glycoprotein and complementary axonal ligands, gangliosides, mediate axon stability in the CNS and PNS: neuropathology and behavioral deficits in single- and double-null mice. Exp Neurol. 2005 Sep;195(1):208-17
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89