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Sequence Detail
Q09143 P30824 (UniProt | EBI) Last sequence update: 1996-10-01
Last annotation update: 2019-09-18
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RecName: Full=High affinity cationic amino acid transporter 1; Short=CAT-1 {ECO:0000250|UniProtKB:P30825}; Short=CAT1;AltName: Full=Ecotropic retroviral leukemia receptor;AltName: Full=Ecotropic retrovirus receptor {ECO:0000303|PubMed:2541
Polypeptide 622 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Slc7a1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 21 4 9 94
Sequence references in MGI J:9786 Albritton LM, et al., A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection. Cell. 1989 May 19;57(4):659-66
J:11385 Kim JW, et al., Transport of cationic amino acids by the mouse ecotropic retrovirus receptor [see comments]. Nature. 1991 Aug 22;352(6337):725-8
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:222036 Hlynialuk CJ, et al., The Mitochondrial Metallochaperone SCO1 Is Required to Sustain Expression of the High-Affinity Copper Transporter CTR1 and Preserve Copper Homeostasis. Cell Rep. 2015 Feb 12;
J:252376 Baker ZN, et al., The mitochondrial metallochaperone SCO1 maintains CTR1 at the plasma membrane to preserve copper homeostasis in the murine heart. Hum Mol Genet. 2017 Dec 1;26(23):4617-4628

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory