Sequence Detail

ID/Version

Q06335 Q80US7 (UniProt | EBI)

Last sequence update: 2011-06-28
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Amyloid beta precursor like protein 2 {ECO:0000250|UniProtKB:Q06481};AltName: Full=Amyloid beta (A4) precursor-like protein 2 {ECO:0000312|MGI:MGI:88047};AltName: Full=Amyloid protein homolog {ECO:0000305};AltName: Full=Amyloid-like protein

Provider

SWISS-PROT

Sequence

Polypeptide 707 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Aplp2	amyloid beta precursor-like protein 2	34	99	3	18

Sequence references in MGI

J:3608 Vidal F, et al., A murine sequence-specific DNA binding protein shows extensive local similarities to the amyloid precursor protein. Biochem Biophys Res Commun. 1992 Dec 30;189(3):1336-41
J:15454 Hanes J, et al., The complete cDNA coding sequence for the mouse CDEI binding protein. Biochim Biophys Acta. 1993 Oct 19;1216(1):154-6
J:29538 von Koch CS, et al., The mouse APLP2 gene. Chromosomal localization and promoter characterization. J Biol Chem. 1995 Oct 27;270(43):25475-80
J:98747 Cappai R, et al., The amyloid precursor protein (APP) of Alzheimer disease and its paralog, APLP2, modulate the Cu/Zn-Nitric Oxide-catalyzed degradation of glypican-1 heparan sulfate in vivo. J Biol Chem. 2005 Apr 8;280(14):13913-20
J:103763 Cao Q, et al., Amyloid precursor proteins anchor CPEB to membranes and promote polyadenylation-induced translation. Mol Cell Biol. 2005 Dec;25(24):10930-9
J:188910 Morris SM, et al., Disabled-2 colocalizes with the LDLR in clathrin-coated pits and interacts with AP-2. Traffic. 2001 Feb;2(2):111-23
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89