Sequence Detail

ID/Version

Q05860 A2AFZ0 Q05859 A2AFY9 (UniProt | EBI)

Last sequence update: 2007-07-24
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Formin-1;AltName: Full=Limb deformity protein;

Provider

SWISS-PROT

Sequence

Polypeptide 1466 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fmn1	formin 1	32	144	4	22

Sequence references in MGI

J:1859 Jackson-Grusby L, et al., A variant limb deformity transcript expressed in the embryonic mouse limb defines a novel formin. Genes Dev. 1992 Jan;6(1):29-37
J:10698 Woychik RP, et al., 'Formins': proteins deduced from the alternative transcripts of the limb deformity gene. Nature. 1990 Aug 30;346(6287):850-3
J:13110 Vogt TF, et al., Formins: phosphoprotein isoforms encoded by the mouse limb deformity locus. Proc Natl Acad Sci U S A. 1993 Jun 15;90(12):5554-8
J:38417 Wang CC, et al., The mouse formin (Fmn) gene: genomic structure, novel exons, and genetic mapping. Genomics. 1997 Feb 1;39(3):303-11
J:87710 Kobielak A, et al., Mammalian formin-1 participates in adherens junctions and polymerization of linear actin cables. Nat Cell Biol. 2004 Jan;6(1):21-30
J:91385 Zuniga A, et al., Mouse limb deformity mutations disrupt a global control region within the large regulatory landscape required for Gremlin expression. Genes Dev. 2004 Jul 1;18(13):1553-64
J:107893 Zhou F, et al., Formin-1 protein associates with microtubules through a peptide domain encoded by exon-2. Exp Cell Res. 2006 Apr 15;312(7):1119-26