Sequence Detail

ID/Version

Q05793 (UniProt | EBI)

Last sequence update: 1995-11-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Basement membrane-specific heparan sulfate proteoglycan core protein; Short=HSPG;Contains: RecName: Full=Endorepellin;Contains: RecName: Full=LG3 peptide;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 3707 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Hspg2	perlecan (heparan sulfate proteoglycan 2)	41	144	3	200

Sequence references in MGI

J:735 Noonan DM, et al., The complete sequence of perlecan, a basement membrane heparan sulfate proteoglycan, reveals extensive similarity with laminin A chain, low density lipoprotein-receptor, and the neural cell adhesion molecule. J Biol Chem. 1991 Dec 5;266(34):22939-47
J:24040 Noonan DM, et al., Identification of cDNA clones encoding different domains of the basement membrane heparan sulfate proteoglycan. J Biol Chem. 1988 Nov 5;263(31):16379-87
J:67299 Arikawa-Hirasawa E, et al., Perlecan is essential for cartilage and cephalic development. Nat Genet. 1999 Nov;23(3):354-8
J:110553 Allen JM, et al., WARP is a novel multimeric component of the chondrocyte pericellular matrix that interacts with perlecan. J Biol Chem. 2006 Mar 17;281(11):7341-9
J:161883 Sasse P, et al., Perlecan is critical for heart stability. Cardiovasc Res. 2008 Dec 1;80(3):435-44
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:333810 Elenbaas JS, et al., SVEP1 is an endogenous ligand for the orphan receptor PEAR1. Nat Commun. 2023 Feb 15;14(1):850