Sequence Detail

ID/Version

Q03311 Q543J3 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Cholinesterase; EC=3.1.1.8;AltName: Full=Acylcholine acylhydrolase;AltName: Full=Butyrylcholine esterase;AltName: Full=Choline esterase II;AltName: Full=Pseudocholinesterase;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 603 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Bche	butyrylcholinesterase	49	98	2	12

Sequence references in MGI

J:41300 Rachinsky TL, et al., Molecular cloning of mouse acetylcholinesterase: tissue distribution of alternatively spliced mRNA species. Neuron. 1990 Sep;5(3):317-27
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:130048 Duysen EG, et al., Sensitivity of butyrylcholinesterase knockout mice to (--)-huperzine A and donepezil suggests humans with butyrylcholinesterase deficiency may not tolerate these Alzheimer's disease drugs and indicates butyrylcholinesterase function in neurotransmission. Toxicology. 2007 Apr 20;233(1-3):60-9
J:156049 Hartmann J, et al., Excessive hippocampal acetylcholine levels in acetylcholinesterase-deficient mice are moderated by butyrylcholinesterase activity. J Neurochem. 2007 Mar;100(5):1421-9
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89