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Sequence Detail
ID/Version
Q03173 Q5D053 P70432 P70430 P70433 P70431 (UniProt | EBI) Last sequence update: 2003-04-23
Last annotation update: 2025-02-05
Sequence
description
from provider
RecName: Full=Protein enabled homolog;AltName: Full=NPC-derived proline-rich protein 1; Short=NDPP-1;
Provider SWISS-PROT
Sequence
Polypeptide 802 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Enah ENAH actin regulator 50 123 3 260
Sequence references in MGI J:3109 Sazuka T, et al., Identification of a developmentally regulated gene in the mouse central nervous system which encodes a novel proline rich protein. Biochim Biophys Acta. 1992 Oct 20;1132(3):240-8
J:43532 Bedford MT, et al., FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands. EMBO J. 1997 May 1;16(9):2376-83
J:44192 Gertler FB, et al., Mena, a relative of VASP and Drosophila Enabled, is implicated in the control of microfilament dynamics. Cell. 1996 Oct 18;87(2):227-39
J:44866 Ermekova KS, et al., The WW domain of neural protein FE65 interacts with proline-rich motifs in Mena, the mammalian homolog of Drosophila enabled. J Biol Chem. 1997 Dec 26;272(52):32869-77
J:53259 Lanier LM, et al., Mena is required for neurulation and commissure formation. Neuron. 1999 Feb;22(2):313-25
J:83872 Tani K, et al., Abl interactor 1 promotes tyrosine 296 phosphorylation of mammalian enabled (Mena) by c-Abl kinase. J Biol Chem. 2003 Jun 13;278(24):21685-92
J:85367 Park KW, et al., Robo4 is a vascular-specific receptor that inhibits endothelial migration. Dev Biol. 2003 Sep 1;261(1):251-67
J:86778 Salazar MA, et al., Tuba, a novel protein containing bin/amphiphysin/Rvs and Dbl homology domains, links dynamin to regulation of the actin cytoskeleton. J Biol Chem. 2003 Dec 5;278(49):49031-43
J:91137 Tanoue T, et al., Mammalian Fat1 cadherin regulates actin dynamics and cell-cell contact. J Cell Biol. 2004 May 24;165(4):517-28
J:230634 Jenzora A, et al., PREL1 provides a link from Ras signalling to the actin cytoskeleton via Ena/VASP proteins. FEBS Lett. 2005 Jan 17;579(2):455-63
J:247397 Polle L, et al., Structural details of human tuba recruitment by InlC of Listeria monocytogenes elucidate bacterial cell-cell spreading. Structure. 2014 Feb 04;22(2):304-14
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory