Sequence Detail

ID/Version

Q03157 A0A0R4IZZ1 Q3U311 Q8VC38 (UniProt | EBI)

Last sequence update: 2021-09-29
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Amyloid beta precursor like protein 1 {ECO:0000250|UniProtKB:P51693};AltName: Full=Amyloid beta (A4) precursor-like protein 1 {ECO:0000312|MGI:MGI:88046};AltName: Full=Amyloid-like protein 1 {ECO:0000250|UniProtKB:P51693}; Short=APLP

Provider

SWISS-PROT

Sequence

Polypeptide 654 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Aplp1	amyloid beta precursor like protein 1	39	108	3	14

Sequence references in MGI

J:3302 Wasco W, et al., Identification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid beta protein precursor. Proc Natl Acad Sci U S A. 1992 Nov 15;89(22):10758-62
J:57129 Homayouni R, et al., Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1. J Neurosci. 1999 Sep 1;19(17):7507-15
J:85533 Yun M, et al., Crystal structures of the Dab homology domains of mouse disabled 1 and 2. J Biol Chem. 2003 Sep 19;278(38):36572-81
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:103763 Cao Q, et al., Amyloid precursor proteins anchor CPEB to membranes and promote polyadenylation-induced translation. Mol Cell Biol. 2005 Dec;25(24):10930-9
J:114052 Matsuda S, et al., c-Jun N-terminal kinase (JNK)-interacting protein-1b/islet-brain-1 scaffolds Alzheimer's amyloid precursor protein with JNK. J Neurosci. 2001 Sep 1;21(17):6597-607
J:188910 Morris SM, et al., Disabled-2 colocalizes with the LDLR in clathrin-coated pits and interacts with AP-2. Traffic. 2001 Feb;2(2):111-23
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89