Sequence Detail

ID/Version

Q03146 (UniProt | EBI)

Last sequence update: 1997-11-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Epithelial discoidin domain-containing receptor 1; Short=Epithelial discoidin domain receptor 1; EC=2.7.10.1;AltName: Full=CD167 antigen-like family member A;AltName: Full=Cell adhesion kinase;AltName: Full=Discoidin receptor

Provider

SWISS-PROT

Sequence

Polypeptide 911 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ddr1	discoidin domain receptor family, member 1	72	106	3	16

Sequence references in MGI

J:3319 Gilardi-Hebenstreit P, et al., An Eph-related receptor protein tyrosine kinase gene segmentally expressed in the developing mouse hindbrain [published erratum appears in Oncogene 1993 Apr;8(4):1103]. Oncogene. 1992 Dec;7(12):2499-506
J:32743 Perez JL, et al., Identification of two isoforms of the Cak receptor kinase that are coexpressed in breast tumor cell lines. Oncogene. 1996 Apr 4;12(7):1469-77
J:68368 Vogel WF, et al., Discoidin domain receptor 1 tyrosine kinase has an essential role in mammary gland development. Mol Cell Biol. 2001 Apr;21(8):2906-17
J:101769 Gross O, et al., DDR1-deficient mice show localized subepithelial GBM thickening with focal loss of slit diaphragms and proteinuria. Kidney Int. 2004 Jul;66(1):102-11
J:109760 Hou G, et al., Tyrosine kinase activity of discoidin domain receptor 1 is necessary for smooth muscle cell migration and matrix metalloproteinase expression. Circ Res. 2002 Jun 14;90(11):1147-9
J:130220 Meyer zum Gottesberge AM, et al., Inner ear defects and hearing loss in mice lacking the collagen receptor DDR1. Lab Invest. 2008 Jan;88(1):27-37