Sequence Detail

ID/Version

Q02956 Q3UHM5 Q7TST7 A2AD76 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Protein kinase C zeta type; EC=2.7.11.13 {ECO:0000269|PubMed:27187150};AltName: Full=nPKC-zeta;

Provider

SWISS-PROT

Sequence

Polypeptide 592 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Prkcz	protein kinase C, zeta	127	140	3	18

Sequence references in MGI

J:3645 Goodnight J, et al., The cDNA sequence, expression pattern and protein characteristics of mouse protein kinase C-zeta. Gene. 1992 Dec 15;122(2):305-11
J:69174 Joberty G, et al., The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42. Nat Cell Biol. 2000 Aug;2(8):531-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:99860 Martin P, et al., Control of T helper 2 cell function and allergic airway inflammation by PKCzeta. Proc Natl Acad Sci U S A. 2005 Jul 12;102(28):9866-71
J:170429 Levy D, et al., Lysine methylation of the NF-kappaB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-kappaB signaling. Nat Immunol. 2011 Jan;12(1):29-36
J:194398 Lee AM, et al., Prkcz null mice show normal learning and memory. Nature. 2013 Jan 17;493(7432):416-9
J:225407 Fritzius T, et al., WD-repeat-propeller-FYVE protein, ProF, binds VAMP2 and protein kinase Czeta. FEBS J. 2007 Mar;274(6):1552-66
J:225409 Fritzius T, et al., A WD-FYVE protein binds to the kinases Akt and PKCzeta/lambda. Biochem J. 2006 Oct 1;399(1):9-20
J:234012 Tsokas P, et al., Compensation for PKMzeta in long-term potentiation and spatial long-term memory in mutant mice. Elife. 2016;5:e14846
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89