Sequence Detail

ID/Version

Q02789 E9QPX8 F8VQE0 E9Q7B5 Q99240 Q3UPG8 (UniProt | EBI)

Last sequence update: 2021-09-29
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Voltage-dependent L-type calcium channel subunit alpha-1S;AltName: Full=Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle;AltName: Full=Dihydropyridine receptor {ECO:0000303|PubMed:16550931, ECO:0000303|PubMed:28351836

Provider

SWISS-PROT

Sequence

Polypeptide 1852 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cacna1s	calcium channel, voltage-dependent, L type, alpha 1S subunit	48	118	4	12

Sequence references in MGI

J:3462 Chaudhari N, A single nucleotide deletion in the skeletal muscle-specific calcium channel transcript of muscular dysgenesis (mdg) mice. J Biol Chem. 1992 Dec 25;267(36):25636-9
J:26177 Perez-Reyes E, et al., Molecular diversity of L-type calcium channels. Evidence for alternative splicing of the transcripts of three non-allelic genes. J Biol Chem. 1990 Nov 25;265(33):20430-6
J:85941 Anderson AA, et al., The novel skeletal muscle sarcoplasmic reticulum JP-45 protein. Molecualr cloning, tissue distribution, developmental expression, and interaction with alpha 1.1 subunit of the voltage-gated calcium channel. J Biol Chem. 2003 Oct 10;278(41):39987-92
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:108926 Anderson AA, et al., The junctional SR protein JP-45 affects the functional expression of the voltage-dependent Ca2+ channel Cav1.1. J Cell Sci. 2006 May 15;119(Pt 10):2145-55
J:261962 Polster A, et al., Stac proteins associate with the critical domain for excitation-contraction coupling in the II-III loop of CaV1.1. J Gen Physiol. 2018 Apr 2;150(4):613-624
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89