Sequence Detail

ID/Version

Q02650 (UniProt | EBI)

Last sequence update: 1993-07-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Paired box protein Pax-5;AltName: Full=B-cell-specific transcription factor; Short=BSAP;

Provider

SWISS-PROT

Sequence

Polypeptide 391 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pax5	paired box 5	46	137	3	24

Sequence references in MGI

J:2251 Adams B, et al., Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis. Genes Dev. 1992 Sep;6(9):1589-607
J:11577 Walther C, et al., Pax: a murine multigene family of paired box-containing genes. Genomics. 1991 Oct;11(2):424-34
J:38813 Nutt SL, et al., Essential functions of Pax5 (BSAP) in pro-B cell development: difference between fetal and adult B lymphopoiesis and reduced V-to-DJ recombination at the IgH locus. Genes Dev. 1997 Feb 15;11(4):476-91
J:113322 Delogu A, et al., Gene repression by Pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells. Immunity. 2006 Mar;24(3):269-81
J:114021 Emelyanov AV, et al., The interaction of Pax5 (BSAP) with Daxx can result in transcriptional activation in B cells. J Biol Chem. 2002 Mar 29;277(13):11156-64