Sequence Detail

ID/Version

Q02257 Q8CGD3 (UniProt | EBI)

Last sequence update: 2005-12-06
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Junction plakoglobin {ECO:0000312|MGI:MGI:96650};AltName: Full=Desmoplakin III;AltName: Full=Desmoplakin-3;

Provider

SWISS-PROT

Sequence

Polypeptide 745 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Jup	junction plakoglobin	123	133	4	196

Sequence references in MGI

J:26079 Butz S, et al., Plakoglobin and beta-catenin: distinct but closely related [letter]. Science. 1992 Aug 21;257(5073):1142-4
J:37378 Butz S, et al., Distinct cadherin-catenin complexes in Ca(2+)-dependent cell-cell adhesion. FEBS Lett. 1994 Nov 28;355(2):195-200
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:141376 Nottebaum AF, et al., VE-PTP maintains the endothelial barrier via plakoglobin and becomes dissociated from VE-cadherin by leukocytes and by VEGF. J Exp Med. 2008 Nov 24;205(12):2929-45
J:233599 Rietscher K, et al., Growth Retardation, Loss of Desmosomal Adhesion, and Impaired Tight Junction Function Identify a Unique Role of Plakophilin 1 In Vivo. J Invest Dermatol. 2016 Jul;136(7):1471-8
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:310979 Dusek RL, et al., Deficiency of the p53/p63 target Perp alters mammary gland homeostasis and promotes cancer. Breast Cancer Res. 2012 Apr 20;14(2):R65