Sequence Detail

ID/Version

Q01279 (UniProt | EBI)

Last sequence update: 1996-02-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Epidermal growth factor receptor {ECO:0000305}; EC=2.7.10.1;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 1210 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Egfr	epidermal growth factor receptor	233	154	3	33

Sequence references in MGI

J:3099 Avivi A, et al., Promoter region of the murine fibroblast growth factor receptor 2 (bek/KGFR) gene. Oncogene. 1992 Oct;7(10):1957-62
J:3764 Paria BC, et al., Expression of the epidermal growth factor receptor gene is regulated in mouse blastocysts during delayed implantation. Proc Natl Acad Sci U S A. 1993 Jan 1;90(1):55-9
J:16986 Luetteke NC, et al., The mouse waved-2 phenotype results from a point mutation in the EGF receptor tyrosine kinase. Genes Dev. 1994 Feb 15;8(4):399-413
J:26833 Threadgill DW, et al., Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype. Science. 1995 Jul 14;269(5221):230-4
J:26834 Sibilia M, et al., Strain-dependent epithelial defects in mice lacking the EGF receptor [published erratum appears in Science 1995 Aug 18;269(5226):909]. Science. 1995 Jul 14;269(5221):234-8
J:27178 Avivi A, et al., Comparison of EGF receptor sequences as a guide to study the ligand binding site. Oncogene. 1991 Apr;6(4):673-6
J:27464 Miettinen PJ, et al., Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor. Nature. 1995 Jul 27;376(6538):337-41
J:34029 Fazioli F, et al., Eps8, a substrate for the epidermal growth factor receptor kinase, enhances EGF-dependent mitogenic signals. EMBO J. 1993 Oct;12(10):3799-808
J:173825 Peng SC, et al., A novel role of CPEB3 in regulating EGFR gene transcription via association with Stat5b in neurons. Nucleic Acids Res. 2010 Nov 1;38(21):7446-57
J:213100 Smith CJ, et al., The E3 ubiquitin ligases RNF126 and Rabring7 regulate endosomal sorting of the epidermal growth factor receptor. J Cell Sci. 2013 Mar 15;126(Pt 6):1366-80
J:220697 Zhong S, et al., Lung Tumor Suppressor GPRC5A Binds EGFR and Restrains Its Effector Signaling. Cancer Res. 2015 May 1;75(9):1801-14
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89