Sequence Detail

ID/Version

Q00899 (UniProt | EBI)

Last sequence update: 1995-11-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Transcriptional repressor protein YY1;AltName: Full=Delta transcription factor;AltName: Full=NF-E1;AltName: Full=UCR-motif DNA-binding protein;AltName: Full=Yin and yang 1; Short=YY-1;

Provider

SWISS-PROT

Sequence

Polypeptide 414 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Yy1	YY1 transcription factor	138	133	4	24

Sequence references in MGI

J:2309 Flanagan JR, et al., Cloning of a negative transcription factor that binds to the upstream conserved region of Moloney murine leukemia virus. Mol Cell Biol. 1992 Jan;12(1):38-44
J:13111 Safrany G, et al., Characterization of the mouse gene that encodes the delta/YY1/NF-E1/UCRBP transcription factor. Proc Natl Acad Sci U S A. 1993 Jun 15;90(12):5559-63
J:130225 Kuzmin A, et al., The PcG gene Sfmbt2 is paternally expressed in extraembryonic tissues. Gene Expr Patterns. 2008 Jan;8(2):107-16
J:155000 Wu S, et al., Loss of YY1 impacts the heterochromatic state and meiotic double-strand breaks during mouse spermatogenesis. Mol Cell Biol. 2009 Dec;29(23):6245-56
J:172975 Wu S, et al., A YY1-INO80 complex regulates genomic stability through homologous recombination-based repair. Nat Struct Mol Biol. 2007 Dec;14(12):1165-72
J:227377 Lu P, et al., The developmental regulator protein Gon4l associates with protein YY1, co-repressor Sin3a, and histone deacetylase 1 and mediates transcriptional repression. J Biol Chem. 2011 May 20;286(20):18311-9
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:326594 Lee KH, et al., SMAD-mediated modulation of YY1 activity regulates the BMP response and cardiac-specific expression of a GATA4/5/6-dependent chick Nkx2.5 enhancer. Development. 2004 Oct;131(19):4709-23