Sequence Detail

ID/Version

Q00612 (UniProt | EBI)

Last sequence update: 2007-03-20
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Glucose-6-phosphate 1-dehydrogenase X; Short=G6PD; EC=1.1.1.49 {ECO:0000269|PubMed:12831846};

Provider

SWISS-PROT

Sequence

Polypeptide 515 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	G6pdx	glucose-6-phosphate dehydrogenase X-linked	65	102	3	8

Sequence references in MGI

J:16964 Zollo M, et al., Sequence of mouse glucose-6-phosphate dehydrogenase cDNA. DNA Seq. 1993;3(5):319-22
J:38406 Toniolo D, et al., The CpG island in the 5' region of the G6PD gene of man and mouse. Gene. 1991 Jun 30;102(2):197-203
J:43103 Kuraguchi M, et al., Somatic mutation of the glucose-6-phosphate dehydrogenase (g6pd) gene in colonic stem cells and crypt restricted loss of G6PD activity. Mutat Res. 1997 Sep 5;379(1):69-75
J:84549 Clarke JL, et al., Murine hexose-6-phosphate dehydrogenase: a bifunctional enzyme with broad substrate specificity and 6-phosphogluconolactonase activity. Arch Biochem Biophys. 2003 Jul 15;415(2):229-34
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:300494 Li M, et al., Aldolase B suppresses hepatocellar carcinogenesis by inhibiting G6PD and pentose phoshate pathways. Nature Cancer. 2020 Jul;1:735-747