Sequence Detail

ID/Version

P98064 Q920S0 Q8CD27 A2RRH9 Q8CIR8 A2RRH8 (UniProt | EBI)

Last sequence update: 2009-04-14
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Mannan-binding lectin serine protease 1; EC=3.4.21.-;AltName: Full=Complement factor MASP-3;AltName: Full=Complement-activating component of Ra-reactive factor;AltName: Full=Mannose-binding lectin-associated serine protease 1;

Provider

SWISS-PROT

Sequence

Polypeptide 704 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Masp1	MBL associated serine protease 1	48	103	3	10

Sequence references in MGI

J:17689 Takahashi A, et al., Presence of a serine protease in the complement-activating component of the complement-dependent bactericidal factor, RaRF, in mouse serum. Biochem Biophys Res Commun. 1993 Feb 15;190(3):681-7
J:17690 Takayama Y, et al., A 100-kDa protein in the C4-activating component of Ra-reactive factor is a new serine protease having module organization similar to C1r and C1s. J Immunol. 1994 Mar 1;152(5):2308-16
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:134537 Takahashi M, et al., Mannose-binding lectin (MBL)-associated serine protease (MASP)-1 contributes to activation of the lectin complement pathway. J Immunol. 2008 May 1;180(9):6132-8
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89