Sequence Detail

ID/Version

P98063 Q6NZM2 (UniProt | EBI)

Last sequence update: 2012-10-03
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Bone morphogenetic protein 1; Short=BMP-1; EC=3.4.24.19;AltName: Full=Mammalian tolloid protein; Short=mTld;AltName: Full=Procollagen C-proteinase; Short=PCP;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 991 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Bmp1	bone morphogenetic protein 1	46	116	4	11

Sequence references in MGI

J:17981 Fukagawa M, et al., Embryonic expression of mouse bone morphogenetic protein-1 (BMP-1), which is related to the Drosophila dorsoventral gene tolloid and encodes a putative astacin metalloendopeptidase. Dev Biol. 1994 May;163(1):175-83
J:36830 Suzuki N, et al., Failure of ventral body wall closure in mouse embryos lacking a procollagen C-proteinase encoded by Bmp1, a mammalian gene related to Drosophila tolloid. Development. 1996 Nov;122(11):3587-95
J:161705 Maruhashi T, et al., Interaction between periostin and BMP-1 promotes proteolytic activation of lysyl oxidase. J Biol Chem. 2010 Apr 23;285(17):13294-303
J:210366 Muir AM, et al., Induced ablation of Bmp1 and Tll1 produces osteogenesis imperfecta in mice. Hum Mol Genet. 2014 Jun 15;23(12):3085-101
J:289165 Wang J, et al., BMP1 and TLL1 Are Required for Maintaining Periodontal Homeostasis. J Dent Res. 2017 May;96(5):578-585