Sequence Detail

ID/Version

P97931 P97509 P97285 Q7TPW8 Q9JIW8 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Uracil-DNA glycosylase {ECO:0000255|HAMAP-Rule:MF_03166}; Short=UDG {ECO:0000255|HAMAP-Rule:MF_03166}; EC=3.2.2.27 {ECO:0000255|HAMAP-Rule:MF_03166};

Provider

SWISS-PROT

Sequence

Polypeptide 306 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ung	uracil DNA glycosylase	53	102	4	18

Sequence references in MGI

J:38558 Nilsen H, et al., Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene. Nucleic Acids Res. 1997 Feb 15;25(4):750-5
J:40051 Svendsen PC, et al., The mouse uracil-DNA glycosylase gene: isolation of cDNA and genomic clones and mapping ung to mouse chromosome 5. Gene. 1997 Apr 21;189(2):175-81
J:62858 Nilsen H, et al., Analysis of uracil-DNA glycosylases from the murine Ung gene reveals differential expression in tissues and in embryonic development and a subcellular sorting pattern that differs from the human homologues. Nucleic Acids Res. 2000 Jun 15;28(12):2277-85
J:79590 Rada C, et al., Immunoglobulin Isotype Switching Is Inhibited and Somatic Hypermutation Perturbed in UNG-Deficient Mice. Curr Biol. 2002 Oct 15;12(20):1748-55
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:100508 Schrader CE, et al., Inducible DNA breaks in Ig S regions are dependent on AID and UNG. J Exp Med. 2005 Aug 15;202(4):561-8
J:167440 Maul RW, et al., Uracil residues dependent on the deaminase AID in immunoglobulin gene variable and switch regions. Nat Immunol. 2011 Jan;12(1):70-6
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89