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Sequence Detail
P97868 Q7TT06 P70287 Q3TUM7 Q8BNY8 Q4U217 Q8R399 Q3UMP7 Q3TTR9 (UniProt | EBI) Last sequence update: 2006-05-16
Last annotation update: 2020-08-12
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RecName: Full=E3 ubiquitin-protein ligase RBBP6; EC=;AltName: Full=Proliferation potential-related protein;AltName: Full=Protein P2P-R;AltName: Full=RING-type E3 ubiquitin transferase RBBP6 {ECO:0000305};AltName: Full=Retinoblastoma-bindin
Polypeptide 1790 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Rbbp6 retinoblastoma binding protein 6, ubiquitin ligase 25 71 6 24
Sequence references in MGI J:38614 Witte MM, et al., The proliferation potential protein-related (P2P-R) gene with domains encoding heterogeneous nuclear ribonucleoprotein association and Rb1 binding shows repressed expression during terminal differentiation. Proc Natl Acad Sci U S A. 1997 Feb 18;94(4):1212-7
J:40929 Simons A, et al., PACT: cloning and characterization of a cellular p53 binding protein that interacts with Rb. Oncogene. 1997 Jan 16;14(2):145-55
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:121586 Li L, et al., PACT is a negative regulator of p53 and essential for cell growth and embryonic development. Proc Natl Acad Sci U S A. 2007 May 8;104(19):7951-6
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:224718 Miotto B, et al., The RBBP6/ZBTB38/MCM10 axis regulates DNA replication and common fragile site stability. Cell Rep. 2014 Apr 24;7(2):575-87
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory