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Sequence Detail
ID/Version
P97868 Q3TUM7 Q4U217 Q7TT06 Q3UMP7 P70287 Q8R399 Q8BNY8 Q3TTR9 (UniProt | EBI) Last sequence update: 2006-05-16
Last annotation update: 2019-05-08
Sequence
description
from provider
RecName: Full=E3 ubiquitin-protein ligase RBBP6; EC=2.3.2.27;AltName: Full=Proliferation potential-related protein;AltName: Full=Protein P2P-R;AltName: Full=RING-type E3 ubiquitin transferase RBBP6 {ECO:0000305};AltName: Full=Retinoblastoma-bindin
Provider SWISS-PROT
Sequence
Polypeptide 1790 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Rbbp6 retinoblastoma binding protein 6, ubiquitin ligase 25 1 6 24
Sequence references in MGI J:38614 Witte MM, et al., The proliferation potential protein-related (P2P-R) gene with domains encoding heterogeneous nuclear ribonucleoprotein association and Rb1 binding shows repressed expression during terminal differentiation. Proc Natl Acad Sci U S A. 1997 Feb 18;94(4):1212-7
J:40929 Simons A, et al., PACT: cloning and characterization of a cellular p53 binding protein that interacts with Rb. Oncogene. 1997 Jan 16;14(2):145-55
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:121586 Li L, et al., PACT is a negative regulator of p53 and essential for cell growth and embryonic development. Proc Natl Acad Sci U S A. 2007 May 8;104(19):7951-6
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:224718 Miotto B, et al., The RBBP6/ZBTB38/MCM10 axis regulates DNA replication and common fragile site stability. Cell Rep. 2014 Apr 24;7(2):575-87

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory