Sequence Detail

ID/Version

P97819 Q99LA9 Q9JK61 (UniProt | EBI)

Last sequence update: 2012-10-31
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=85/88 kDa calcium-independent phospholipase A2; Short=CaI-PLA2; EC=3.1.1.4 {ECO:0000269|PubMed:18937505};AltName: Full=2-lysophosphatidylcholine acylhydrolase; EC=3.1.1.5 {ECO:0000250|UniProtKB:O60733};AltName: Full=G

Provider

SWISS-PROT

Sequence

Polypeptide 807 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pla2g6	phospholipase A2, group VI	83	98	3	51

Sequence references in MGI

J:62053 Balboa MA, et al., Identity between the Ca2+-independent phospholipase A2 enzymes from P388D1 macrophages and Chinese hamster ovary cells. J Biol Chem. 1997 Mar 28;272(13):8576-80
J:132853 Shinzawa K, et al., Neuroaxonal dystrophy caused by group VIA phospholipase A2 deficiency in mice: a model of human neurodegenerative disease. J Neurosci. 2008 Feb 27;28(9):2212-20
J:133472 Bao S, et al., Glucose homeostasis, insulin secretion, and islet phospholipids in mice that overexpress iPLA2beta in pancreatic beta-cells and in iPLA2beta-null mice. Am J Physiol Endocrinol Metab. 2008 Feb;294(2):E217-29
J:144546 Carper MJ, et al., Skeletal muscle group VIA phospholipase A2 (iPLA2beta): expression and role in fatty acid oxidation. Biochemistry. 2008 Nov 18;47(46):12241-9
J:174587 Beck G, et al., Neuroaxonal dystrophy in calcium-independent phospholipase A2beta deficiency results from insufficient remodeling and degeneration of mitochondrial and presynaptic membranes. J Neurosci. 2011 Aug 3;31(31):11411-11420
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89