Sequence Detail

ID/Version

P97801 O09092 (UniProt | EBI)

Last sequence update: 1997-05-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Survival motor neuron protein;

Provider

SWISS-PROT

Sequence

Polypeptide 288 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Smn1	survival motor neuron 1	48	127	4	23

Sequence references in MGI

J:38576 Viollet L, et al., cDNA isolation, expression, and chromosomal localization of the mouse survival motor neuron gene (Smn). Genomics. 1997 Feb 15;40(1):185-8
J:39673 DiDonato CJ, et al., Cloning, characterization, and copy number of the murine survival motor neuron gene: homolog of the spinal muscular atrophy-determining gene. Genome Res. 1997 Apr;7(4):339-52
J:42813 Schrank B, et al., Inactivation of the survival motor neuron gene, a candidate gene for human spinal muscular atrophy, leads to massive cell death in early mouse embryos. Proc Natl Acad Sci U S A. 1997 Sep 2;94(18):9920-5
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:170079 Fallini C, et al., The Survival of Motor Neuron (SMN) Protein Interacts with the mRNA-Binding Protein HuD and Regulates Localization of Poly(A) mRNA in Primary Motor Neuron Axons. J Neurosci. 2011 Mar 9;31(10):3914-25
J:189067 Lotti F, et al., An SMN-Dependent U12 Splicing Event Essential for Motor Circuit Function. Cell. 2012 Oct 12;151(2):440-54
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89