Sequence Detail

ID/Version

P97772 Q6AXG4 Q9EPV6 (UniProt | EBI)

Last sequence update: 2003-04-11
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Metabotropic glutamate receptor 1; Short=mGluR1;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 1199 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Grm1	glutamate receptor, metabotropic 1	83	115	4	30

Sequence references in MGI

J:58626 Zhu H, et al., Cloning of novel splice variants of mouse mGluR1. Brain Res Mol Brain Res. 1999 Nov 10;73(1-2):93-103
J:136786 Ihara M, et al., Sept4, a component of presynaptic scaffold and Lewy bodies, is required for the suppression of alpha-synuclein neurotoxicity. Neuron. 2007 Feb 15;53(4):519-33
J:211964 Ady V, et al., Type 1 metabotropic glutamate receptors (mGlu1) trigger the gating of GluD2 delta glutamate receptors. EMBO Rep. 2014 Jan;15(1):103-9
J:241495 Charette JR, et al., A Chemical Mutagenesis Screen Identifies Mouse Models with ERG Defects. Adv Exp Med Biol. 2016;854:177-83
J:263376 Trinidad JC, et al., Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Mol Cell Proteomics. 2006 May;5(5):914-22
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:354172 Dadak S, et al., mGlu1 receptor canonical signaling pathway contributes to the opening of the orphan GluD2 receptor. Neuropharmacology. 2017 Mar 15;115:92-99
J:354174 Benamer N, et al., GluD1, linked to schizophrenia, controls the burst firing of dopamine neurons. Mol Psychiatry. 2018 Mar;23(3):691-700