Sequence Detail

ID/Version

P97494 O09166 Q8VCS5 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Glutamate--cysteine ligase catalytic subunit {ECO:0000305}; EC=6.3.2.2 {ECO:0000269|PubMed:16608839};AltName: Full=GCS heavy chain;AltName: Full=Gamma-ECS;AltName: Full=Gamma-glutamylcysteine synthetase;

Provider

SWISS-PROT

Sequence

Polypeptide 637 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Gclc	glutamate-cysteine ligase, catalytic subunit	104	128	3	14

Sequence references in MGI

J:41485 Reid LL, et al., Molecular cloning and sequencing of the cDNA encoding the catalytic subunit of mouse glutamate-cysteine ligase. Biochim Biophys Acta. 1997 Jun 26;1352(3):233-7
J:41600 Kang Y, et al., Cloning/brain localization of mouse glutamylcysteine synthetase heavy chain mRNA. Neuroreport. 1997 May 27;8(8):2053-60
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89