Sequence Detail

ID/Version

P97430 O09082 O09081 (UniProt | EBI)

Last sequence update: 1997-05-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Antileukoproteinase; Short=ALP;AltName: Full=Secretory leukocyte protease inhibitor {ECO:0000303|PubMed:9039268};Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 131 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slpi	secretory leukocyte peptidase inhibitor	43	99	4	10

Sequence references in MGI

J:38212 Jin FY, et al., Secretory leukocyte protease inhibitor: a macrophage product induced by and antagonistic to bacterial lipopolysaccharide. Cell. 1997 Feb 7;88(3):417-26
J:39194 Zitnik RJ, et al., The cloning and characterization of a murine secretory leukocyte protease inhibitor cDNA. Biochem Biophys Res Commun. 1997 Mar 27;232(3):687-97
J:43912 Abe T, et al., Bacterial pneumonia causes augmented expression of the secretory leukoprotease inhibitor gene in the murine lung. Am J Respir Crit Care Med. 1997 Oct;156(4 Pt 1):1235-40
J:65241 Ashcroft GS, et al., Secretory leukocyte protease inhibitor mediates non-redundant functions necessary for normal wound healing. Nat Med. 2000 Oct;6(10):1147-53
J:82214 Nakamura A, et al., Increased susceptibility to LPS-induced endotoxin shock in secretory leukoprotease inhibitor (SLPI)-deficient mice. J Exp Med. 2003 Mar 3;197(5):669-74
J:132933 Nishimura J, et al., Potent antimycobacterial activity of mouse secretory leukocyte protease inhibitor. J Immunol. 2008 Mar 15;180(6):4032-9
J:220133 McCartney-Francis N, et al., Aberrant host defense against Leishmania major in the absence of SLPI. J Leukoc Biol. 2014 Nov;96(5):917-29
J:269644 Zhu J, et al., Conversion of proepithelin to epithelins: roles of SLPI and elastase in host defense and wound repair. Cell. 2002 Dec 13;111(6):867-78