About   Help   FAQ
Sequence Detail
ID/Version
P97428 O09091 P97420 Q80V16 (UniProt | EBI) Last sequence update: 1997-05-01
Last annotation update: 2019-02-13
Sequence
description
from provider
RecName: Full=Regulator of G-protein signaling 16; Short=RGS16;AltName: Full=A28-RGS14P;AltName: Full=Retinal-specific RGS; Short=RGS-r {ECO:0000303|PubMed:8917514};AltName: Full=Retinally abundant regulator of G-protein signaling;
Provider SWISS-PROT
Sequence
Polypeptide 201 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Rgs16 regulator of G-protein signaling 16 14 3 9 9
Sequence references in MGI J:36569 Chen CK, et al., RGS-r, a retinal specific RGS protein, binds an intermediate conformation of transducin and enhances recycling. Proc Natl Acad Sci U S A. 1996 Nov 12;93(23):12885-9
J:39294 Chen C, et al., Characterization of a novel mammalian RGS protein that binds to Galpha proteins and inhibits pheromone signaling in yeast. J Biol Chem. 1997 Mar 28;272(13):8679-85
J:41940 Buckbinder L, et al., The p53 tumor suppressor targets a novel regulator of G protein signaling. Proc Natl Acad Sci U S A. 1997 Jul 22;94(15):7868-72
J:46072 Snow BE, et al., Cloning of a retinally abundant regulator of G-protein signaling (RGS-r/RGS16): genomic structure and chromosomal localization of the human gene. Gene. 1998 Jan 12;206(2):247-53
J:228419 Druey KM, et al., Amino-terminal cysteine residues of RGS16 are required for palmitoylation and modulation of Gi- and Gq-mediated signaling. J Biol Chem. 1999 Jun 25;274(26):18836-42
J:248218 Slep KC, et al., Molecular architecture of Galphao and the structural basis for RGS16-mediated deactivation. Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6243-8

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/09/2019
MGI 6.13
The Jackson Laboratory