Sequence Detail

ID/Version

P97428 Q80V16 P97420 O09091 (UniProt | EBI)

Last sequence update: 1997-05-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Regulator of G-protein signaling 16; Short=RGS16;AltName: Full=A28-RGS14P;AltName: Full=Retinal-specific RGS; Short=RGS-r {ECO:0000303|PubMed:8917514};AltName: Full=Retinally abundant regulator of G-protein signaling;

Provider

SWISS-PROT

Sequence

Polypeptide 201 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Rgs16	regulator of G-protein signaling 16	14	100	4	13

Sequence references in MGI

J:36569 Chen CK, et al., RGS-r, a retinal specific RGS protein, binds an intermediate conformation of transducin and enhances recycling. Proc Natl Acad Sci U S A. 1996 Nov 12;93(23):12885-9
J:39294 Chen C, et al., Characterization of a novel mammalian RGS protein that binds to Galpha proteins and inhibits pheromone signaling in yeast. J Biol Chem. 1997 Mar 28;272(13):8679-85
J:41940 Buckbinder L, et al., The p53 tumor suppressor targets a novel regulator of G protein signaling. Proc Natl Acad Sci U S A. 1997 Jul 22;94(15):7868-72
J:46072 Snow BE, et al., Cloning of a retinally abundant regulator of G-protein signaling (RGS-r/RGS16): genomic structure and chromosomal localization of the human gene. Gene. 1998 Jan 12;206(2):247-53
J:228419 Druey KM, et al., Amino-terminal cysteine residues of RGS16 are required for palmitoylation and modulation of Gi- and Gq-mediated signaling. J Biol Chem. 1999 Jun 25;274(26):18836-42
J:248218 Slep KC, et al., Molecular architecture of Galphao and the structural basis for RGS16-mediated deactivation. Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6243-8