Sequence Detail

ID/Version

P97411 E9QLS3 Q99M40 P97954 Q9R2C4 P97362 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Islet cell autoantigen 1;AltName: Full=69 kDa islet cell autoantigen; Short=ICA69;AltName: Full=Islet cell autoantigen p69; Short=ICAp69; Short=p69;

Provider

SWISS-PROT

Sequence

Polypeptide 478 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ica1	islet cell autoantigen 1	42	110	3	15

Sequence references in MGI

J:37708 Gaedigk R, et al., Genomic organization and transcript analysis of ICAp69, a target antigen in diabetic autoimmunity. Genomics. 1996 Dec 15;38(3):382-91
J:39784 Karges W, et al., Molecular cloning of murine ICA69: diabetes-prone mice recognize the human autoimmune-epitope, Tep69, conserved in splice variants from both species. Biochim Biophys Acta. 1997 Apr 12;1360(2):97-101
J:65514 Pilon M, et al., The diabetes autoantigen ICA69 and its caenorhabditis elegans homologue, ric-19, are conserved regulators of neuroendocrine secretion. Mol Biol Cell. 2000 Oct;11(10):3277-88
J:83526 Winer S, et al., ICA69(null) nonobese diabetic mice develop diabetes, but resist disease acceleration by cyclophosphamide. J Immunol. 2002 Jan 1;168(1):475-82
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89