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Sequence Detail
P97377 O55105 (UniProt | EBI) Last sequence update: 2000-05-30
Last annotation update: 2018-02-28
from provider
RecName: Full=Cyclin-dependent kinase 2; EC= {ECO:0000269|PubMed:23853094};AltName: Full=Cell division protein kinase 2;
Polypeptide 346 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Cdk2 cyclin-dependent kinase 2 76 14 9 25
Sequence references in MGI J:85230 Ortega S, et al., Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice. Nat Genet. 2003 Sep;35(1):25-31
J:86203 Berthet C, et al., Cdk2 knockout mice are viable. Curr Biol. 2003 Oct 14;13(20):1775-85
J:168213 Wu CL, et al., Cables enhances cdk2 tyrosine 15 phosphorylation by Wee1, inhibits cell growth, and is lost in many human colon and squamous cancers. Cancer Res. 2001 Oct 1;61(19):7325-32
J:219103 Wang GL, et al., Liver tumors escape negative control of proliferation via PI3K/Akt-mediated block of C/EBP alpha growth inhibitory activity. Genes Dev. 2004 Apr 15;18(8):912-25

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory