Sequence Detail

ID/Version

P97306 (UniProt | EBI)

Last sequence update: 1997-05-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=SH3 and cysteine-rich domain-containing protein;AltName: Full=Src homology 3 and cysteine-rich domain-containing protein;

Provider

SWISS-PROT

Sequence

Polypeptide 403 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Stac	src homology three (SH3) and cysteine rich domain	20	98	3	6

Sequence references in MGI

J:42308 Suzuki H, et al., Stac, a novel neuron-specific protein with cysteine-rich and SH3 domains. Biochem Biophys Res Commun. 1996 Dec 24;229(3):902-9
J:222015 Nelson BR, et al., Skeletal muscle-specific T-tubule protein STAC3 mediates voltage-induced Ca2+ release and contractility. Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):11881-6
J:251999 Rzhepetskyy Y, et al., A Cav3.2/Stac1 molecular complex controls T-type channel expression at the plasma membrane. Channels (Austin). 2016 Sep 2;10(5):346-354
J:252007 Campiglio M, et al., STAC3 stably interacts through its C1 domain with CaV1.1 in skeletal muscle triads. Sci Rep. 2017 Jan 23;7:41003
J:261962 Polster A, et al., Stac proteins associate with the critical domain for excitation-contraction coupling in the II-III loop of CaV1.1. J Gen Physiol. 2018 Apr 2;150(4):613-624