About   Help   FAQ
Due to maintenance, access to MGI maybe intermittent on Thu, May 23 at 7:30 AM ET.
Sequence Detail
ID/Version
P97305 Q60896 (UniProt | EBI) Last sequence update: 1997-05-01
Last annotation update: 2019-02-13
Sequence
description
from provider
RecName: Full=Nuclear factor of activated T-cells, cytoplasmic 3; Short=NF-ATc3; Short=NFATc3;AltName: Full=NFATx;AltName: Full=T-cell transcription factor NFAT4; Short=NF-AT4;
Provider SWISS-PROT
Sequence
Polypeptide 1075 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Nfatc3 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3 59 12 9 56
Sequence references in MGI J:28305 Ho SN, et al., NFATc3, a lymphoid-specific NFATc family member that is calcium-regulated and exhibits distinct DNA binding specificity. J Biol Chem. 1995 Aug 25;270(34):19898-907
J:38327 Liu J, et al., Calcineurin-dependent nuclear translocation of a murine transcription factor NFATx: molecular cloning and functional characterization. Mol Biol Cell. 1997 Jan;8(1):157-70
J:79608 Wilkins BJ, et al., Targeted Disruption of NFATc3, but Not NFATc4, Reveals an Intrinsic Defect in Calcineurin-Mediated Cardiac Hypertrophic Growth. Mol Cell Biol. 2002 Nov;22(21):7603-13
J:84138 Bushdid PB, et al., NFATc3 and NFATc4 are required for cardiac development and mitochondrial function. Circ Res. 2003 Jun 27;92(12):1305-13
J:119549 Yang XY, et al., Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/07/2019
MGI 6.14
The Jackson Laboratory