Sequence Detail

ID/Version

P97305 Q60896 (UniProt | EBI)

Last sequence update: 1997-05-01
Last annotation update: 2019-02-13

Sequence description from provider

RecName: Full=Nuclear factor of activated T-cells, cytoplasmic 3; Short=NF-ATc3; Short=NFATc3;AltName: Full=NFATx;AltName: Full=T-cell transcription factor NFAT4; Short=NF-AT4;

Provider

SWISS-PROT

Sequence

Polypeptide 1075 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nfatc3	nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3	59	12	9	56

Sequence references in MGI

J:28305 Ho SN, et al., NFATc3, a lymphoid-specific NFATc family member that is calcium-regulated and exhibits distinct DNA binding specificity. J Biol Chem. 1995 Aug 25;270(34):19898-907
J:38327 Liu J, et al., Calcineurin-dependent nuclear translocation of a murine transcription factor NFATx: molecular cloning and functional characterization. Mol Biol Cell. 1997 Jan;8(1):157-70
J:79608 Wilkins BJ, et al., Targeted Disruption of NFATc3, but Not NFATc4, Reveals an Intrinsic Defect in Calcineurin-Mediated Cardiac Hypertrophic Growth. Mol Cell Biol. 2002 Nov;22(21):7603-13
J:84138 Bushdid PB, et al., NFATc3 and NFATc4 are required for cardiac development and mitochondrial function. Circ Res. 2003 Jun 27;92(12):1305-13
J:119549 Yang XY, et al., Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37