Sequence Detail

ID/Version

P86547 P04641 (UniProt | EBI)

Last sequence update: 2010-07-13
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Osteocalcin-2; Short=OG2 {ECO:0000303|PubMed:8684484};AltName: Full=Bone Gla protein 2; Short=BGP2;AltName: Full=Gamma-carboxyglutamic acid-containing protein 2;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 95 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Bglap2	bone gamma-carboxyglutamate protein 2	48	167	3	11

Sequence references in MGI

J:8426 Celeste AJ, et al., Isolation of the human gene for bone gla protein utilizing mouse and rat cDNA clones. EMBO J. 1986 Aug;5(8):1885-90
J:16166 Rahman S, et al., Multiple copies of the bone-specific osteocalcin gene in mouse and rat. Endocrinology. 1993 Dec;133(6):3050-3
J:16427 Desbois C, et al., The mouse osteocalcin gene cluster contains three genes with two separate spatial and temporal patterns of expression. J Biol Chem. 1994 Jan 14;269(2):1183-90
J:34440 Ducy P, et al., Increased bone formation in osteocalcin-deficient mice. Nature. 1996 Aug 1;382(6590):448-52
J:126780 Lee NK, et al., Endocrine regulation of energy metabolism by the skeleton. Cell. 2007 Aug 10;130(3):456-69
J:164596 Ferron M, et al., Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism. Cell. 2010 Jul 23;142(2):296-308
J:165982 Fulzele K, et al., Insulin receptor signaling in osteoblasts regulates postnatal bone acquisition and body composition. Cell. 2010 Jul 23;142(2):309-19
J:170888 Oury F, et al., Endocrine regulation of male fertility by the skeleton. Cell. 2011 Mar 4;144(5):796-809
J:205218 Oury F, et al., Maternal and offspring pools of osteocalcin influence brain development and functions. Cell. 2013 Sep 26;155(1):228-41
J:246056 Khrimian L, et al., Gpr158 mediates osteocalcin's regulation of cognition. J Exp Med. 2017 Oct 02;214(10):2859-2873