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Sequence Detail
ID/Version
P80560 Q1RLJ1 P70328 O09134 (UniProt | EBI) Last sequence update: 2011-07-27
Last annotation update: 2014-03-19
Sequence
description
from provider
RecName: Full=Receptor-type tyrosine-protein phosphatase N2; Short=R-PTP-N2; EC=3.1.3.48;AltName: Full=PTP IA-2beta;AltName: Full=Protein tyrosine phosphatase-NP; Short=PTP-NP;Flags: Precursor;
Provider SWISS-PROT
Sequence
Polypeptide 1001 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Ptprn2 protein tyrosine phosphatase, receptor type, N polypeptide 2 18 6 4 5
Sequence references in MGI J:34182 Chiang MK, et al., PTP-NP, a new member of the receptor protein tyrosine phosphatase family, implicated in development of nervous system and pancreatic endocrine cells. Development. 1996 Jul;122(7):2239-50
J:34575 Lu J, et al., Identification of a second transmembrane protein tyrosine phosphatase, IA-2beta, as an autoantigen in insulin-dependent diabetes mellitus: precursor of the 37-kDa tryptic fragment. Proc Natl Acad Sci U S A. 1996 Mar 19;93(6):2307-11
J:91889 Kubosaki A, et al., Targeted disruption of the IA-2beta gene causes glucose intolerance and impairs insulin secretion but does not prevent the development of diabetes in NOD mice. Diabetes. 2004 Jul;53(7):1684-91

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory