Sequence Detail

ID/Version

P70700 Q3UMX7 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=DNA-directed RNA polymerase I subunit RPA2; Short=RNA polymerase I subunit 2; EC=2.7.7.6 {ECO:0000250|UniProtKB:Q9H9Y6};AltName: Full=DNA-directed RNA polymerase I 135 kDa polypeptide; Short=RPA135;

Provider

SWISS-PROT

Sequence

Polypeptide 1135 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Polr1b	polymerase (RNA) I polypeptide B	47	99	3	19

Sequence references in MGI

J:35801 Seither P, et al., Molecular cloning of RPA2, the gene encoding the second largest subunit of mouse RNA polymerase I. Genomics. 1996 Oct 1;37(1):135-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:268520 Zhang Q, et al., Evolutionarily-conserved MZIP2 is essential for crossover formation in mammalian meiosis. Commun Biol. 2018;1:147
J:285969 Liu H, et al., SCRE serves as a unique synaptonemal complex fastener and is essential for progression of meiosis prophase I in mice. Nucleic Acids Res. 2019 Jun 20;47(11):5670-5683
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:297328 Zhang Q, et al., SPO16 binds SHOC1 to promote homologous recombination and crossing-over in meiotic prophase I. Sci Adv. 2019 Jan;5(1):eaau9780