Sequence Detail

ID/Version

P70414 (UniProt | EBI)

Last sequence update: 1997-02-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Sodium/calcium exchanger 1;AltName: Full=Na(+)/Ca(2+)-exchange protein 1;AltName: Full=Solute carrier family 8 member 1;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 970 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slc8a1	solute carrier family 8 (sodium/calcium exchanger), member 1	125	156	4	13

Sequence references in MGI

J:49463 Kim I, et al., Cloning of the mouse cardiac Na(+)-Ca2+ exchanger and functional expression in Xenopus oocytes. Ann N Y Acad Sci. 1996 Apr 15;779:126-8
J:65985 Wakimoto K, et al., Targeted disruption of Na+/Ca2+ exchanger gene leads to cardiomyocyte apoptosis and defects in heartbeat. J Biol Chem. 2000 Nov 24;275(47):36991-8
J:102564 Wakimoto K, et al., Na+/Ca2+ exchanger-deficient mice have disorganized myofibrils and swollen mitochondria in cardiomyocytes. Comp Biochem Physiol B Biochem Mol Biol. 2003 May;135(1):9-15
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89