Sequence Detail

ID/Version

P70392 Q9QX51 Q3TYN3 (UniProt | EBI)

Last sequence update: 2000-05-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Ras-specific guanine nucleotide-releasing factor 2; Short=Ras-GRF2;AltName: Full=Ras guanine nucleotide exchange factor 2;

Provider

SWISS-PROT

Sequence

Polypeptide 1189 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Rasgrf2	RAS protein-specific guanine nucleotide-releasing factor 2	30	99	4	9

Sequence references in MGI

J:38516 Fam NP, et al., Cloning and characterization of Ras-GRF2, a novel guanine nucleotide exchange factor for Ras. Mol Cell Biol. 1997 Mar;17(3):1396-406
J:75928 Fernandez-Medarde A, et al., Targeted disruption of Ras-Grf2 shows its dispensability for mouse growth and development. Mol Cell Biol. 2002 Apr;22(8):2498-504
J:90111 Tian X, et al., Developmentally regulated role for Ras-GRFs in coupling NMDA glutamate receptors to Ras, Erk and CREB. EMBO J. 2004 Apr 7;23(7):1567-75
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:105650 Li S, et al., Distinct roles for Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) and Ras-GRF2 in the induction of long-term potentiation and long-term depression. J Neurosci. 2006 Feb 8;26(6):1721-9
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89