Sequence Detail

ID/Version

P70349 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Adenosine 5'-monophosphoramidase HINT1 {ECO:0000250|UniProtKB:P49773}; EC=3.9.1.- {ECO:0000250|UniProtKB:P49773};AltName: Full=Desumoylating isopeptidase HINT1 {ECO:0000305|PubMed:31088288}; EC=3.4.22.- {ECO:0000250|UniProtKB

Provider

SWISS-PROT

Sequence

Polypeptide 126 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Hint1	histidine triad nucleotide binding protein 1	61	101	4	85

Sequence references in MGI

J:50522 Klein MG, et al., Characterization of PKCI and comparative studies with FHIT, related members of the HIT protein family. Exp Cell Res. 1998 Oct 10;244(1):26-32
J:84504 Su T, et al., Deletion of histidine triad nucleotide-binding protein 1/PKC-interacting protein in mice enhances cell growth and carcinogenesis. Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7824-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:298016 Cortes-Montero E, et al., The Axonal Motor Neuropathy-Related HINT1 Protein Is a Zinc- and Calmodulin-Regulated Cysteine SUMO Protease. Antioxid Redox Signal. 2019 Sep 1;31(7):503-520