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Sequence Detail
ID/Version
P70315 (UniProt | EBI) Last sequence update: 1997-02-01
Last annotation update: 2020-04-22
Sequence
description
from provider
RecName: Full=Wiskott-Aldrich syndrome protein homolog; Short=WASp;
Provider SWISS-PROT
Sequence
Polypeptide 520 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Was Wiskott-Aldrich syndrome 42 72 5 12
Sequence references in MGI J:29221 Derry JM, et al., The mouse homolog of the Wiskott-Aldrich syndrome protein (WASP) gene is highly conserved and maps near the scurfy (sf) mutation on the X chromosome. Genomics. 1995 Sep 20;29(2):471-7
J:36722 Quilliam LA, et al., Isolation of a NCK-associated kinase, PRK2, an SH3-binding protein and potential effector of Rho protein signaling. J Biol Chem. 1996 Nov 15;271(46):28772-6
J:46222 Wu Y, et al., Tyrosine phosphorylation regulates the SH3-mediated binding of the Wiskott-Aldrich syndrome protein to PSTPIP, a cytoskeletal-associated protein. J Biol Chem. 1998 Mar 6;273(10):5765-70
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:283192 Cao H, et al., FCHSD1 and FCHSD2 are expressed in hair cell stereocilia and cuticular plate and regulate actin polymerization in vitro. PLoS One. 2013;8(2):e56516

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2020
MGI 6.15
The Jackson Laboratory